Maria Angela Ardinghelli (1730–1825) was an Italian translator, mathematician, and physicist.

Maria was born in Naples into a noble family of Florentine origin. She studied philosophy and physical-mathematical sciences under the physicist and mathematician Pietro Della Torre and Vito Caravelli.

As was obligatory for the aristocratic women of the time, Maria Angela was a literate poet and Latinist, as well as expert of mathematical physics. She belonged to the circle of the prince of Tarsia, founded in 1747, which, in intellectual circles in Naples, had the strongest association to Newton, experimental physics and electricity. The library and the laboratory of Tarsia was to be of much use to her.

An expert in mathematical physics, she is mainly known for her translation into Italian of English physiologist Stephen Hales’s book, Vegetable Staticks (1727), a classic text in plant physiology. She also performed scientific experiments inspired by the translations.

She corresponded with leading scientists of the time, including, to name a few, the mathematician and astronomer and physicist Alexis Claude Clairaut and Jean-Antoine Nollet.